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The Moo’D Study: A randomised controlled trial of A2 vs conventional dairy products in women with low mood.

This trial evaluated the comparative effects of consumption of dairy products containing A2 beta-casein versus conventional dairy (i.e. containing both A1 and A2 beta-casein) on symptoms of psychological distress in women with low mood. ‘The Moo’D Study’ is a 16-week, superiority, 1:1 parallel group, triple-blinded, randomised controlled trial. Ninety women with low mood (Patient Health Questionnaire score ≥ 5) will be randomised to consume either A2 beta-casein only or conventional dairy products. The primary outcome, symptoms of psychological distress, were measured by the 21-item Depression, Anxiety, and Stress Scale. Secondary outcomes include symptoms of depression, anxiety, and stress, severity of low mood, cognition, gut microbiota composition, gut symptomatology, markers of immune function, gut inflammation, systemic metabolites, endothelial integrity and oxidative stress, body composition, perceived wellbeing, sleep, quality of life, resource use and cost-effectiveness.

Subjects
Anxiety / Depression / Mental Health / Other mental health disorders
Date made available
Immediately following publication. No end date.
Data set type
IPD
ANZCTR reference number
Publication
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Dataset Access Link
Protocol
Researchers requiring more information regarding the study protocol are encouraged to contact the Principle Investigator via email.
Data dictionary
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