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COPE-A: A randomised controlled trial of integrated psychological therapy for traumatic stress and substance use among adolescents aged 12-25 years

The dataset from the COPE-A trial captures detailed variables assessing the effects of trauma-focused cognitive-behavioral therapy on adolescents with PTSD and substance use issues. Core variables include DSM-5 diagnostic criteria for PTSD, measured through the Clinician-Administered PTSD Scale for Children and Adolescents (CAPS-CA-5), and substance dependence criteria assessed by the Diagnostic Interview Schedule for Children (DISC-5). Secondary variables track trauma-related cognitive changes (Child Post-Traumatic Cognitions Inventory, CPTCI) and emotional regulation (Emotion Regulation Questionnaire, ERQ-CA), with symptom severity and remission assessed at baseline, 4-month, and 12-month follow-ups. Additional variables monitor substance use patterns (Timeline Follow Back), distress tolerance (Distress Tolerance Scale), and self-compassion (SCS-SF). Measures of functional outcomes, therapeutic alliance (Working Alliance Inventory, WAI-SR), and client satisfaction (CSQ) are included, alongside adverse event reporting and session-specific changes in PTSD symptoms and cravings. This dataset enables a thorough analysis of clinical outcomes using DSM-5 criteria and other standardized measures across therapy sessions.

Subjects
Addiction / Anxiety / Mental Health
Date made available
Data under embargo
Data set type
No IPD sharing as per ethics requirements
ANZCTR reference number
Publication
Mills, K.L., Barrett, E., Back, S.E., Cobham, V.E., Bendall, S., Perrin, S., Brady, K.T., Ross, J., Peach, N., Kihas, I. and Cassar, J., 2020. Randomised controlled trial of integrated trauma-focused psychotherapy for traumatic stress and substance use among adolescents: trial protocol. BMJ open, 10(11), p.e043742.
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